|
KMID : 0882420140860020242
|
|
Korean Journal of Medicine
2014 Volume.86 No. 2 p.242 ~ p.246
|
|
|
Acute Myeloid Leukemia with Persistent Marrow Aplasia after Chemotherapy Treated with Reduced-Intensity Allogeneic Stem Cell Transplantation
|
|
Yoon Hyun-Hwa
Hong Jun-Shik
Kim Su-Young
Lee Dong-Min
Park Jinny
Ahn Jeong-Yeal
Lee Jae-Hoon
|
|
|
Abstract
|
|
|
|
Persistent bone marrow aplasia after intensive chemotherapy is uncommon, but is one of the fatal complications in patients with acute myeloid leukemia (AML). Although allogeneic hematopoietic stem cell transplantation (HSCT) is considered to be contraindicated for patients who have hematologic diseases with serious infections, such as bacterial septicemia or invasive fungal diseases, combined with prolonged neutropenia due to frequent morbidity and mortality, such risks can be overcome by non-myeloablative conditioning and best supportive care. Here, we report an AML patient with persistent marrow aplasia after induction therapy, treated successfully with reduced-intensity allogeneic HSCT despite severe bacterial and fungal infections.
|
|
|
KEYWORD
|
|
|
Acute myeloid leukemia, Stem cell transplantation, Aplastic anemia, Neutropenia, Chemotherapy
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|